Sex-Chromosome Biology and Evolution
Sex chromosomes, such as the X and Y of mammals, are involved in sex-determination in many animal and plant species. Their sex specificity leads them to evolve differently from other chromosomes, and acquire distinctive biological properties. The Vicoso group investigates how sex chromosomes evolve over time, and what biological forces are driving their patterns of differentiation.
The Vicoso group is interested in understanding several aspects of the biology of sex chromosomes, and the evolutionary processes that shape their peculiar features. By combining the use of next-generation sequencing technologies with studies in several model and non-model organisms, they can address a variety of standing questions, such as: Why do some Y chromosomes degenerate while others remain homomorphic, and how does this relate to the extent of sexual dimorphism of the species? What forces drive some species to acquire global dosage compensation of the X, while others only compensate specific genes? What are the frequency and molecular dynamics of sex-chromosome turnover?
On this site:
Sex chromosome turnover and conservation | Dosage compensation in female-heterogametic species | Gene expression evolution in sexual and asexual species
Lasne C, Elkrewi MN, Toups MA, Layana Franco LA, Macon A, Vicoso B. The scorpionfly (Panorpa cognata) genome highlights conserved and derived features of the peculiar dipteran X chromosome. Molecular Biology and Evolution. View
Toups MA, Vicoso B. 2023. The X chromosome of insects likely predates the origin of class Insecta. Evolution. 77(11), 2504–2511. View
Puixeu Sala G. 2023. The molecular basis of sexual dimorphism: Experimental and theoretical characterization of phenotypic, transcriptomic and genetic patterns of sex-specific adaptation. Institute of Science and Technology Austria. View
ReX-Link: Beatriz Vicoso
since 2015 Assistant Professor, Institute of Science and Technology Austria (ISTA)
2009 – 2014 Postdoc, University of California, Berkeley, USA
2010 PhD, University of Edinburgh, Scotland, UK
2017 Member of the Young Academy of the Austrian Academy of Sciences
2016 ERC Starting Grant
2016 FWF Standalone Grant
2011 DeLill Nasser Travel Award from the Genetics Society of America